This massive PowerShell script is a textbook for Windows registry hacking. It is heavily commented, meaning you can learn why each tweak works.
By hosting your own tweaks on GitHub, you can re-apply your perfect Windows 10 setup in under 30 seconds after a clean install. The best Windows 10 registry tweaks on GitHub are not about "hacking" your computer; they are about reclaiming control. Repositories like W10-Privacy and Chris Titus Tech have done the heavy lifting of testing thousands of registry keys so you don't have to brick your OS.
[HKEY_LOCAL_MACHINE\SOFTWARE\Policies\Microsoft\Windows\Personalization] "NoLockScreen"=dword:00000001 Source: Disassembler0/Win10InitialSetupScript
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This is arguably the gold standard. While it is a full executable, the source code reveals every single registry key it touches.