If you are still stuck, the EA Answers HQ (Archived FIFA 16 section) contains legacy threads. However, the links and steps provided here are the final word on getting your beloved FIFA 16 running on Windows 10/11.
You click the play button. The screen flashes. Then, nothing happens—except a pop-up box insisting that Origin (or the EA App) is missing, even though you know you just installed it. fifa 16 origin not installed error fix pc link
Install the EA App + VC++ 2013 runtimes + Disable Core Isolation. For offline players, Simlink is your best friend. If you are still stuck, the EA Answers